{[['
']]}
']]}
BOOK DETAILS
| This comprehensive guide to polycystic kidney disease captures the growing knowledge of this common, potentially-fatal and hereditary disease. The first two sections of the book provide an overview of PKD gene structures, mutations and pathophysiologic mechanisms. This is followed by chapters focused on PKD’s clinical features, including renal and extrarenal manifestations, and appropriate management of patients. The final section covers current clinical trials and emerging therapies in PKD. Authored by experts in the field, this book provides the clinician and researcher with critical information on basic and translational science and clinical approaches in one concise resource. Table of contents : Front Matter ....Pages i-xiii Front Matter ....Pages 1-1 Classical Polycystic Kidney Disease: Gene Structures and Mutations and Protein Structures and Functions (Emilie Cornec-Le Gall, Peter C. Harris)....Pages 3-26 Bardet-Biedl Syndrome (Yangfan P. Liu, Nicholas Katsanis)....Pages 27-50 Cystic Kidney Diseases Associated with Increased Cancer Risk: Tuberous Sclerosis Complex, Von Hippel-Lindau, and Birt-Hogg-DubĂ© (John J. Bissler)....Pages 51-66 Front Matter ....Pages 67-67 Aberrant Cellular Pathways in PKD (Alison Grazioli, Patricia Outeda, Terry Watnick)....Pages 69-86 Cilia and Polycystic Kidney Disease (Dawn E. Landis, Scott J. Henke, Bradley K. Yoder)....Pages 87-110 The Role of Inflammation and Fibrosis in Cystic Kidney Disease (James C. Harms, Cheng Jack Song, Michal Mrug)....Pages 111-129 Front Matter ....Pages 131-131 Imaging-Based Diagnosis of Autosomal Dominant Polycystic Kidney Disease (Young-Hwan Hwang, Moumita Barua, Anna McNaught, Korosh Khalili, York Pei)....Pages 133-142 Renal Structural Involvement in Autosomal Dominant Polycystic Kidney Disease: Cyst Growth and Total Kidney Volume – Lessons from the Consortium for Radiologic Imaging of Polycystic Kidney Disease (CRISP) (Frederic Rahbari-Oskoui, Harpreet Bhutani, Olubunmi Williams, Ankush Mittal, Arlene Chapman)....Pages 143-153 Renal Complications: Pain, Infection, and Nephrolithiasis (Cristian Riella, Peter G. Czarnecki, Theodore I. Steinman)....Pages 155-169 Extrarenal Manifestations of Autosomal Dominant Polycystic Kidney Disease: Polycystic Liver Disease (Fouad T. Chebib, Marie C. Hogan)....Pages 171-195 Other Extrarenal Manifestations of Autosomal Dominant Polycystic Kidney Disease (Charles L. Edelstein)....Pages 197-206 Front Matter ....Pages 207-207 Role of Renin-Angiotensin-Aldosterone System Inhibition in Autosomal Dominant Polycystic Kidney Disease (Pranav S. Garimella, Dana C. Miskulin)....Pages 209-218 Vasopressin Receptor Antagonism in PKD (Maria V. Irazabal, Vicente E. Torres)....Pages 219-227 End-Stage Renal Disease in Patients with Autosomal Dominant Polycystic Kidney Disease (Ahd Al Khunaizi, Ahsan Alam)....Pages 229-241 Management of ADPKD Today (Ronald D. Perrone, Osama W. Amro)....Pages 243-262 Back Matter ....Pages 263-273 |
Chapisha Maoni